Declining levels of NAD+ are considered a hallmark of aging.
Boosting NAD+ levels through NR and NMN administration extends the life of several organisms, including yeast, worms, and mice, and positively impacts metabolic function in animals.
In humans, NR supplements are considered safe to take in the short-term, and effectively and reliably boost NAD+ levels.
NAD may improve blood pressure and aortic stiffness, is available to skeletal muscle, and exerts anti-inflammatory properties.